Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cfl1  cofilin 1, non-muscle   (Synonyms: Cof, cofilin, n-cofilin)
Results	Reference
1*	J:125317 Bellenchi GC, Gurniak CB, Perlas E, Middei S, Ammassari-Teule M, Witke W, N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex. Genes Dev. 2007 Sep 15;21(18):2347-57
1	J:268912 Ducharme P, Zarruk JG, David S, Paquin J, The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain. Mol Cell Neurosci. 2018 Oct;92:104-113
1	J:333965 Fan M, Liu Y, Shang Y, Xue Y, Liang J, Huang Z, JADE2 Is Essential for Hippocampal Synaptic Plasticity and Cognitive Functions in Mice. Biol Psychiatry. 2022 Nov 15;92(10):800-814
1*	J:276652 Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F, Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
1	J:282364 Frendo ME, da Silva A, Phan KD, Riche S, Butler SJ, The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons. J Neurosci. 2019 Nov 20;39(47):9316-9327
1	J:154032 Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F, Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. PLoS One. 2009;4(10):e7641
1	J:233564 Gurniak CB, Chevessier F, Jokwitz M, Jonsson F, Perlas E, Richter H, Matern G, Boyl PP, Chaponnier C, Furst D, Schroder R, Witke W, Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance. Eur J Cell Biol. 2014 May-Jun;93(5-6):252-66
1*	J:96452 Gurniak CB, Perlas E, Witke W, The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol. 2005 Feb 1;278(1):231-41
1	J:331698 Ishii K, Kohno T, Sakai K, Hattori M, Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation. Mol Cell Neurosci. 2022 Nov 23;124:103794
1*	J:314903 Jiang X, Lv J, Zhou R, Xiang X, The effect of cofilin 1 expression and phosphorylation dynamics on cell fate determination and neuron maturation in neural stem cells. Neurosci Lett. 2021 Nov 1;764:136292
1	J:208651 Louvi A, Nishimura S, Gunel M, Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar;141(6):1404-15
1	J:178484 Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV, Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011 Dec 1;360(1):30-43
1*	J:63356 Mohri K, Takano-Ohmuro H, Nakashima H, Hayakawa K, Endo T, Hanaoka K, Obinata T, Expression of cofilin isoforms during development of mouse striated muscles. J Muscle Res Cell Motil. 2000 Jan;21(1):49-57
1	J:161853 Mokalled MH, Johnson A, Kim Y, Oh J, Olson EN, Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development. Development. 2010 Jul;137(14):2365-74
1*	J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55
1*	J:239230 Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, Xiang Y, Liu W, Chen J, Yi Z, Li L, Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017 Jan 27;292(4):1438-1448
1	J:330575 Yamada S, Mizukoshi T, Tokunaga A, Sakakibara SI, Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development. PLoS Genet. 2022 Oct;18(10):e1010438
1	J:276133 Yang CY, Yu TH, Wen WL, Ling P, Hsu KS, Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation. J Neurosci. 2019 Jun 19;39(25):4959-4975
1	J:211364 Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, Lu S, Chen J, Yang Z, A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice. Am J Pathol. 2014 Jul;184(7):1967-80
1	J:300786 Zhang Z, Ye M, Li Q, You Y, Yu H, Ma Y, Mei L, Sun X, Wang L, Yue W, Li R, Li J, Zhang D, The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. Cell Rep. 2019 Oct 1;29(1):49-61.e7